Deep brain stimulation is an experimental procedure for treatment-resistant depression. Some results show promise, but blinded trials had limited success. Ethical questions center on vulnerability: especially on whether depressed patients can weigh the risks and benefits effectively, whether depression causes “desperation,” and whether media portrayals create unrealistic hopes. We interviewed 24 psychiatric inpatients with treatment-resistant depression, qualitatively analyzing their comments. Most had minimal interest in deep brain stimulators. Some might consider them if their depression worsened, if alternatives were exhausted, or (...) if the evidence were stronger. Fears focused on the surgery, adverse effects, and the novelty of the device. Patients felt the depression interfered with their ability to weigh the risks and benefits. Patients seemed highly attuned to the risks, and were skeptical that the treatment would be effective. We conclude that ethical concerns about vulnerability remain, yet patients with treatment-resistant depression were thoughtful and cautious about trying a novel therapy. (shrink)

We describe in some detail how to build an infinite computing machine within a continuous Newtonian universe. The relevance of our construction to the Church-Turing thesis and the Platonist-Intuitionist debate about the nature of mathematics is also discussed.

The regular increase in the proportion of resolved feet in the iambic trimeters of Euripides' later plays was first commented upon in 1807 by J. Gottfried Hermann, who therefrom deduced the principle that the date of any play of Euripides could be directly determined from the frequency of its resolutions. This criterion he restated in several of his works in the following years, and when Elmsley objected that it was of uncertain value on account of the small number of plays (...) of certain date by which it might be verified, he replied with a strong defence of his case: he did not, however, develop his principle in detail or give figures in its support. The first scholar to publish the totals of trisyllabic feet in each play was Zirndorfer: relying largely on these, he produced a chronology of Euripides' dramatic composition in several respects superior to any predecessor's. His conclusions were questioned by C. F. W. Müller, who, while accepting Hermann's thesis as being in general correct, doubted its reliability for determining the exact period of a tragedy's composition. Consequently, although he gave the totals of trisyllabic feet en passant, Müller made no attempt to suggest dates. At almost the same time as Müller's treatise appeared, J. Rumpel published an article giving a full and detailed list of references to all trisyllabic feet in Euripides: from this evidence he divided the dramas into four age-groups, but did not go so far as to assign specific dates. (shrink)

'The problem of the twentieth-century is the problem of the color-line.' Originally published in 1903, The Souls of Black Folk is a classic study of race, culture, and education at the turn of the twentieth century. With its singular combination of essays, memoir, and fiction, this book vaulted W. E. B. Du Bois to the forefront of American political commentary and civil rights activism. The Souls of Black Folk is an impassioned, at times searing account of the situation of African (...) Americans in the United States. Du Bois makes a forceful case for the access of African Americans to higher education, memorably extols the achievements of black culture (above all the spirituals or 'sorrow songs'), and advances the provocative and influential argument that due to the inequalities and pressures of the 'race problem', African American identity is characterized by 'double consciousness'. This edition includes a valuable appendix of other writing by Du Bois, which sheds light on his attitudes and intentions. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more. (shrink)

We argue that the experimental verification of Newtonian mechanics and of non-relativistic quantum mechanics do not imply that space is continuous. This provides evidence against the realist interpretation of the most mathematical parts of physics.

Hastings Center Report, Volume 52, Issue S1, Page S83-S88, March‐April 2022.